Survey of Lung Transplant Community's Views on Primary Graft Dysfunction
نویسندگان
چکیده
منابع مشابه
Primary Graft Dysfunction After Lung Transplantation.
Primary graft dysfunction is a form of acute injury after lung transplantation that is associated with significant short- and long-term morbidity and mortality. Multiple mechanisms contribute to the pathogenesis of primary graft dysfunction, including ischemia reperfusion injury, epithelial cell death, endothelial cell dysfunction, innate immune activation, oxidative stress, and release of infl...
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Primary graft dysfunction (PGD) is a major complication following lung transplantation. We reported that anti-type V collagen (col(V)) T cell immunity was strongly associated with PGD. However, the role of preformed anti-col(V) Abs and their potential target in PGD are unknown. Col(V) immune serum, purified IgG or B cells from col(V) immune rats were transferred to WKY rat lung isograft recipie...
متن کاملLong Term Impact of Primary Graft Dysfunction after Lung Transplantation
According to the International Society for Heart and Lung Transplantation (ISHLT) Registry, graft failure accounted for 24.7% of deaths within 30 days of transplantation among adult lung recipients between 1992 and 2012 [1]. Although important details distinguishing different causes of early graft failure may be missing from the Registry data, it is likely that primary graft dysfunction (PGD) i...
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It would have seemed that the problem is relatively simple: graft rejection or coronary artery disease after cardiac transplantation induces edema, inflammation, myocyte damage, necrosis, ischemia, and sometimes fibrosis, resulting in ventricular systolic and diastolic dysfunction. These should be detectable by echocardiography; yet, the quest for a sufficiently sensitive, specific, and conclus...
متن کاملEchocardiographic Detection of Heart Transplant Graft Dysfunction
It would have seemed that the problem is relatively simple: graft rejection or coronary artery disease after cardiac transplantation induces edema, inflammation, myocyte damage, necrosis, ischemia, and sometimes fibrosis, resulting in ventricular systolic and diastolic dysfunction. These should be detectable by echocardiography; yet, the quest for a sufficiently sensitive, specific, and conclus...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2016
ISSN: 1600-6135
DOI: 10.1111/ajt.13552